Product name

Identification of peptides and other organic substances inhibiting the virus- host cell-interaction

Summary

A method for identification of short coiled-coil sequences which are binding the viral envelope protein.

Organization name

ipal GmbH

Profile

The coiled-coil interaction is basic to the fusion of virus membrane with the target membrane. The identification of highly specific, short peptides which can inhibit the virus-host cell interaction without induction of an immune response could lead to the development of new antiviral pharmaceuticals.

The inventors developed a method of identification using SPOT-Technology on cellulose membranes. Investigation on HA2 virus (Influenza) and Tuberculosis are in process, studies on HIV, SIV, Ebola should follow.

Benefits

• Virus-host cell interaction can be inhibited by highly specific peptides
• Application possible for viral diseases like
  • HIV
  • Influenza
• Application possible for bacterial diseases like
  • M. tuberculosis

A German and PCT application have been filed.

The technology was developed at Charité- University Hospital, Berlin and is offerd by IPAL.

ipal GmbH
Rafaela Kunz
rafaela.kunz(at)ipal.de

About IPAL

The ipal GmbH patent agency assesses and markets the inventions of scientists in the area of Life Sciences and Physics & Engineering from Charité-Universitätsmedizin (University Medicine), Robert Koch Institute, Deutsches Herzzentrum (German Heart Institute), Bundesanstalt für Materialprüfung (BAM - Federal Institute for Materials Research and Testing), the Zuse Institute as well as the Paul Ehrlich Institute, Langen and the Jacobs University Bremen. IPAL provides all of the services necessary - from the assessment of patentable technologies to a comprehensive patent protection all the way to the evaluation of sales returns potentials on the market and successful commercialisation through the use of licensing agreements.

Description File

 05085_Virus_Host_TA.pdf

URL

http://www.ipal.de/en/technology_offers/life_sciences/

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