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Product name

Novel pyrimidine derivatives for the treatment of picorna viral infections

Summary

4-amino-3-arylamino-6-arylpyrazolo[3,4-d]-pyrimidine derivatives

Organization name

IP Bewertungs AG (IPB)

Profile

Comprehensive pharmacological and toxicological studies revealed that the API is well-tolerated in rats and mice even at elevated doses as well as after long-term exposure (1-month). First experiments in a Coxsackie B3 virus (CVB3)-induced myocarditis mouse-model also provided strong evidence for the API’s in vivo efficacy.

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